Testimonials More

Why did you decide to have LASIK? Why did you choose Dr. Wang? How has your life changed since your LASIK procedure? What is your advice for people considering LASIK? - Click to see more

Special promotions More
Home Print This Page

Safety and Effectiveness of Thin-flap LASIK Using a Femtosecond Laser and Microkeratome in the Correction of High Myopia in Chinese Patients

Journal of Refractive Surgery  Vol. 26   No. 2   February 2010

Haiyan Li, PhD, MD; Tong Sun, MD; Ming Wang, PhD, MD and Jialiang Zhao, PhD, MD


To establish safety and effectiveness of thin-flap LASIK using a femtosecond laser and microkeratome in correcting high myopia in Chinese patients.


Two hundred seventy-four eyes of 148 Chinese patients with high myopia whose spherical equivalent refraction (SE) ranged from –6.12 to –15.75 diopters (D) received thin-flap LASIK with the VISX S4 IR excimer laser system. Corneal flaps were created with a femtosecond laser (15-kHz IntraLase, 134 eyes of 76 patients, target flap thickness 100 µm) and Moria M2 microkeratome (90-µm head, 140 eyes of 72 patients, target flap thickness 110 µm). Clinical outcomes were assessed with uncorrected (UCVA) and best spectacle-corrected visual acuity (BSCVA), manifest refraction, wavefront aberrometry, Schirmer tests, and tear break-up time (TBUT) at 1 day, 1 week, and 1 and 3 months postoperatively.


At 3 months, both groups showed comparable clinical outcomes in most parameters assessed, including the percent of postoperative UCVA better than or equal to preoperative BSCVA (P=.642), mean residual spherical equivalent refraction (P=.448), mean Schirmer test (P=.950), and mean TBUT (P=.867). Postoperative coma, trefoil, and spherical aberration were similar in both groups (P=.202, P=.898, and P=.890, respectively). Both groups had a similar percent of eyes with a change of SE of <1.00 D (P=.284).


Thin-flap LASIK with a femtosecond laser and microkeratome are both safe and effective for the correction of high myopia in Chinese patients. Femtosecond laser shows similar predictability, stability, and induction of higher order aberrations to the microkeratome. [J Refract Surg. 2010;26:99-106.]



From the Department of Ophthalmology, Shanghai AIER Eye Hospital, Shanghai, China (Li, Sun); Wang Vision 3D Cataract and LASIK Center, Nashville, Tenn (Wang); and the Department of Ophthalmology, Peking Union Medical College Hospital, Tsinghua University, Beijing, China (Zhao).

The authors have no commercial, financial, or proprietary interest in the materials presented herein.

Correspondence: Haiyan Li, PhD, MD, No. 1286 Hongqiao Rd, Shanghai, China 200336. Tel: 86 137 64523896; Fax: 86 021 62190332; E-mail:

Received: February 11, 2008; Accepted: February 10, 2009

Posted online: March 18, 2009




Home | News | Twitter | Testimonials | Financing | About Us | Site Map | Contact Us | Find Us | Why Choose WVI | Patient forms| Dr. Wang | Staff Doctors
For physicians | Optometric residency | Corneal surgical fellowship | Formal CE programs | IOL calculation | Co-managers | How to choose a surgeon

Dr. Ming Wang, Eye Surgeon, provides laser vision correction, 3D LASIK, laser cataract and many advanced laser eye surgeries to patients in the Nashville, TN area
and all over the US and world. Dr. Wang's celebrity LASIK patients:  Dolly Parton, Charlie Daniels, Kenny Chesney, 3 Doors Down, Naomi Judd, and more...

This site is for informational purposes only. It is not intended to be medical advice. If you would like professional medical advice about any laser eye surgery procedure, please
schedule an appointment or attend our next Free LASIK and Cataract Seminar in Nashville, Tennessee.

Copyright ©2002-2013. Wang Vision 3D Cataract and LASIK Center. 1801 West End Ave. Ste 1150, Nashville, TN, 37203, USA
(615)321-8881 (O) (615)321-8874(Fax) email: